Vybrané Projekty, Koncepty

Web App / Bioinformatics

Monoclonal Antibody Structures

Interactive, Template-Guided Platform for mABs (re)construction

Python Modeller Muscle Django
mABs Project
CADD / Structural Design

Computer Aided Drug Design

Combining Computational Biology with Experimental Pharmacology and Medicinal Chemistry

Virtual Screening Docking ADMET profiling
CADD General
Concept

Nucleotide Analogs

Rational Design and Optimization of 6-thio-GTP Analogs

Ligand-Based Design Conformational Search DMPK
Nucleotide Modifications
CADD / Structural Design

Discovery of Glucocorticoid Receptor Modulators

Dual-Pathway Targeting via Virtual Screening and Combinatorial Chemistry.

Structure-Based Design Database Mining
Glucocorticoid - Receptors
Bioinformatics / Data Science

Monoclonal Antibody Analysis

Automated structural-domain composition profiling of mABs

Python PDB BLAST HMMER
Analysis of mABs
Systems Biology / Kinetics

Dynamics of IFN-γ Signaling

Equation-based simulation of immune regulation and macrophage activation pathways.

Kinetics Modeling ODEs OpenModelica
IFN-γ and Immune Response